A brief post here. I am simply listing a few genes/SNPs that associate with HDL-cholesterol in a manner modified by physical activity.
One can see from the above table (click for a larger view) that results of physical activity modifying the effects of APOE alleles is not consistent across populations. There are different risk alleles in the different studies. The EUROSPAN study under PubMed ID 20066028 did not give specifics of levels of physical activity nor identify the risk alleles.
If there is something that interests you in terms of measures of metabolic health (along the lines of heart disease, diabetes, blood lipids), just ask and I'll see what I can provide.